Image Guided Thermal Therapy

The BSD-2000 3D/MR employs the next generation of non-invasive thermometry.
MR images are translated to map and visualize temperature, allowing
for precision placement of the hyperthermic heating zone.
Not for sale in the United States.
Increase Workflow with
easier patient access

The Sigma Eye/MR applicator's side opening allows for more natural
patient access. The unit can be removed and stored, allowing
the MR system to be used for traditional imaging.
Not for sale in the United States.
Temperature Imaging during treatment

There is no interruption during the hyperthermia/imaging process. The patient remains in the
MR system during the full course of treatment. A water bolus is used to make connection
between the RF signal and the patient. Circulated water can be cooled or heated for patient comfort.
Not for sale in the United States.

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Realtime Heat Zone Steering

A great benefit of image-guided thermal therapy
is the ability to validate and electronically steer the heat zone to
ensure proper treatment placement and target temperature.
Not for sale in the United States.

Learn More Data Sheet

Who is Pyrexar Medical

By leveraging the therapeutic power of focused heat, Pyrexar Medical seeks to revolutionize cancer care. We aim to enhance traditional cancer therapies, with clinically proven and effective options.

We are committed to continuing to advance these pioneering solutions, as we strive to redefine the landscape of cancer care for a brighter and healthier future.

Clinical Evidence Matters

Randomized clinical trials (RCT’s) have show significant improvement in clinical outcomes when hyperthermia was added to radiotherapy and/or chemotherapy. Experts in clinical hyperthermia held a consensus meeting (Kadota Fund International Forum 2004) about the evidence of the published clinical results of the RCT’s. Level 1 evidence was found for bladder cancer, breast cancer, cervical cancer, cancer of the esophagus, lymph nodes of head and neck tumors, rectum cancer, soft tissue sarcoma, malignant melanoma, glioblastoma multiform, and various superficial cancers.

Hyperthermia Clinical Trials

Hyperthermia chart demonstrating proven clinical results

Cancer Immune Modulaton

Heat Matters

According to the standards set by the Society of Thermal Medicine (STM), European Society for Hyperthermic Oncology (ESHO) and the Asian Society of Hyperthermic Oncology (ASHO), the benefits of hyperthermia are fully realized when the tumor temperature reaches 39-43 degrees Celsius.

Heat is known to kill cancer cells, shrink tumor size, increase radiosensitivity, inhibit DNA repair, oxygenate hypoxic tumors, produce heat shock proteins, and increase disease-free survival.

Show Me the Data

Clinical Study Reveals Increased Longevity

An independent study published in the Journal of the American Medical Association (JAMA) reports on a 10 year patient follow-up to a phase III clinical study on a Soft Tissue Sarcoma Study. In addition to higher CR, the addition of hyperthermia increased the median long-term survival rate from 6.2 to 15.4 years

Read the Study

Infographic of Soft Tissue Sarcoma Study

Performing interstitial hyperthermia requires the use for the BSD-500 built-in treatment planning program. Using this software, the size and shape of the tumor can be traced on a grid on the computers screen. Treatment plans can ten be made by simulating the placement of antennae in and around the tumor. The power and phase of each channel can be set and adjusted on the screen. Each change in placement, power or phase will display the new simulated heating pattern.

Trace tumor and position applicators

trace tumors

Calculate energy distribution pattern

trace tumors

Adjust phase and power to achieve desired heating pattern

adjust phase

Transfer settings to hyperthermia treatment screen

transfer settings

Benefits of Hyperthermia in Cancer Treatment*

Effects Tumor Cell

In the delicate micro-environment of a cancer cell, heat can lead to direct cell death, shrinking tumor size for easier surgical resection.

Low Toxicity

Very low to no toxicity is often reported when administering hyperthermia. There is no known toxicity build-up from multiple treatments.

Increase Blood Flow

Increased blood flow and perfusion at the tumor site promote oxygenation, increasing radiosensitivity.

Survival Benefit

A phase III clinical study shows an increased survival benefit when hyperthermia was added to traditional therapies.

Inhibits DNA Repair

Hyperthermia, in combination with Radiotherapy, will inhibit the DNA repair cycle of radiation-damaged cancer cells.

Heat Shock Proteins

Tumor cells express heat shock proteins when exposed to hyperthermic temperatures allowing tumor-specific antigens to reach the immune system.

Our Products

BSD 500 Superficial and Interstitial Hyperthermia Cancer Treatment System

BSD-500 Superficial/Interstitial

The BSD-500 Superficial/Interstitial Hyperthermia system is a versatile, fully self-contained treatment device in a mobile configuration for maximum treatment flexibility of superficial tumors within 4cm of the skin surface or used interstitially as an adjunct to brachytherapy

BSD-500

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BSD 2000 Deep Regional Hyperthermia Cancer Treatment System

BSD-2000 Deep Regional

The BSD-2000 Deep Regional Hyperthermia System provides focused RF hyperthermia (heating) at any depth of the body using four-channel - 8 dipoles phased array antennas. 3 Applicator Options • Electronic Steering

BSD-2000

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BSD 2000 3D Deep Regional Hyperthermia Cancer Treatment System

BSD-2000 3D Deep Regional

The BSD-2000 3D Deep Regional Hyperthermia System provides focused RF hyperthermia (heating) at any depth of the body using 12 channel - 24 dipoles phased array antennas. 2 Applicator Options • Electronic Steering

BSD-2000

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BSD 2000 3D MR Guided Deep Regional Hyperthermia Cancer Treatment System

BSD-2000 3D/MR Deep Regional

The BSD-2000 3DMR Deep Regional Hyperthermia System provides focused RF hyperthermia (heating) at any depth of the body using 12 channel - 24 dipoles phased array antennas. 2 Applicator Options • Electronic Steering • Image-Guided Thermal Therapy.

BSD-2000 3D/MR

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© 2015 - 2025 Pyrexar Medical

* Source: Front. Oncol., 12 June 2020 | https://doi.org/10.3389/fonc.2020.00819