Researchers are combining traditional cancer treatment therapies in order to increase a patients chance of surviving cancer. Even a few percentage points in tumor response can represent a significant benefit in saving of a life. Dr. Niloy Datta. from Kantonsspital Aarau AG,Switzerland, presented his recently published meta-analysis paper at a conference held at the Scientific-Research Institute of Oncology, St. Petersburg, Russia.
In the analysis Dr. Datta compared results for treating advanced cancer of the cervix using combination therapies. When comparing Chemotherapy with Radiotherapy (CTRT) versus radiation alone, the odds benefit of complete tumor response was 1.43. When comparing Hyperthermia with Radiotherapy (HTRT) versus radiation alone, the odds of complete tumor response to 2.68.
Hyperthermia plus Radiation therapy provided superior outcomes without the increase in acute toxicity found with Chemotherapy.
Go to minute 25:00 on the presentation to see the overall Odds and risk ratios presented.
The paper was published August 12th, 2016 in the International Journal of Hyperthermia, Hyperthermia and radiotherapy with or without chemotherapy in locally advanced cervical cancer: a systematic review with conventional and network meta-analyses. Niloy R. Datta, Susanne Rogers, Dirk Klingbiel, Silvia Gómez, Emsad Puric & Stephan Bodis